This guidance document is a call to action for local governments to lead as catalysts of change in the shift toward a circular economy. It equips cities with practical tools to accelerate the transition at the local level and directly capture its benefits. By tackling the root cause of environmental degradation, overconsumption of natural resources, cities can drive systemic change. Applying circular economy principles such as reducing, reusing, and extending product lifecycles enables cities to reshape consumption patterns across society. Instead of responding to the impacts of overconsumption, cities can take a proactive approach by adopting key urban policy instruments. These include fostering cultural and behavioural change, using urban planning to improve access to circular consumption options, leveraging direct incentives for businesses and consumers, and implementing regulatory measures that support circular practices. This guide is a valuable resource for cities and regions, particularly during the Map and Design phases of Circular Systemic Solutions deployment.